Drug intelligence / Profile preview

amoxicillin + clarithromycin + pantoprazole

Development stage
Unknown
Lead developer
Sun Pharmaceutical Industries
Modality
Small Molecules
Administration
Oral
01

Overview

Amoxicillin + clarithromycin + pantoprazole is a triple therapy combination used primarily to treat peptic ulcer disease caused by Helicobacter pylori infection. Each component has a specific role in the treatment: - **Amoxicillin**: A bactericidal antibiotic that prevents the formation of bacterial cell walls necessary for survival - **Clarithromycin**: A bacteriostatic antibiotic that inhibits protein synthesis required for bacterial growth - **Pantoprazole**: A proton pump inhibitor that blocks the gastric proton pump enzyme, reducing stomach acid production This combination therapy typically achieves H. pylori eradication rates of 93-94% when administered for 7-14 days. It helps heal duodenal ulcers and gastritis while preventing recurrence by eliminating the underlying bacterial infection.

Brand names
Pantocid HPPantop HPSet HPEvoxil-HPLaritova-HPMy-HPPleze-HPPantolime-HPPantonac-HPBiopeg-HP
Other names
amoxicillin + clarithromycin + pantoprazolepantoprazole + amoxycillin + clarithromycinclarithromycin + pantoprazole + amoxicillin
02

Targets

Bacterial 50S ribosomal subunitATP4A (Potassium–transporting ATPase alpha chain 1)

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