Drug intelligence / Profile preview

amoxicillin + clavulanic acid + cefotiam

Development stage
Unknown
Lead developer
GSK
Modality
Small Molecules
Administration
Oral, Intravenous, Intramuscular
01

Overview

This appears to be a combination of three antimicrobial agents: amoxicillin (a penicillin-type antibiotic), clavulanic acid (a beta-lactamase inhibitor), and cefotiam (a cephalosporin antibiotic). While amoxicillin + clavulanic acid is a well-established combination used to treat various bacterial infections including those of the ears, lungs, sinuses, skin, and urinary tract, the addition of cefotiam to this combination is not documented in the provided search results. Amoxicillin works by stopping bacterial growth, while clavulanic acid prevents bacteria from destroying amoxicillin by inhibiting beta-lactamase enzymes. Cefotiam would likely provide additional coverage against certain bacteria as a cephalosporin antibiotic.

02

Targets

Class A BL (Class A beta-lactamase)PBP (Penicillin-binding protein family)

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