amoxicillin clavulanate

Amoxicillin clavulanate is a combination antibiotic consisting of amoxicillin, a penicillin-class antibiotic, and clavulanic acid (clavulanate), a beta-lactamase inhibitor. Amoxicillin works by inhibiting bacterial cell wall synthesis, leading to bacterial death. However, some bacteria produce beta-lactamase enzymes that can inactivate amoxicillin; clavulanic acid inhibits these enzymes, thereby extending the spectrum of activity of amoxicillin against beta-lactamase-producing organisms. This combination is used to treat various bacterial infections including those of the ear, lungs (such as pneumonia and bronchitis), sinuses, skin and soft tissue, urinary tract infections, animal bites, and others. It is available in oral and intravenous formulations[1][2][3][4][5]. The drug was first approved for use in the United States in 1984[5].

Brand names

AugmentinAugmentin ES-600Augmentin XRAmoclanAlti-Amoxi ClavApo-Amoxi ClavNovo-Clavamoxin 125Novo-Clavamoxin125Novo-Clavamoxin-125Novo-Clavamoxin 250Novo-Clavamoxin250Novo-Clavamoxin-250Ratio-Amoxi Clav 250

Other names

co-amoxiclavamox-clav