Drug intelligence / Profile preview

AMP-105

Development stage
Preclinical
Lead developer
Amphastar Pharmaceuticals
Modality
Peptides
01

Overview

AMP-105 is a first-in-class, endogenous-derived peptide being developed by Amphastar Pharmaceuticals (specifically its subsidiary Amphastar France Pharmaceuticals) for the treatment of various solid tumors and hematologic malignancies. Licensed from Nanjing Anji Biotechnology, the drug utilizes a novel mechanism of action to suppress cell growth and inhibit metastasis. Preclinical studies have demonstrated broad anti-tumor activity across several indications, including head and neck squamous cell carcinoma (HNSCC), hepatocellular carcinoma (HCC), lymphoma, and multiple myeloma. The product is based on an endogenous peptide discovery that potentially suppresses the growth and metastasis of multiple poorly treated cancers.

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