ampelopsis radix extract

Ampelopsis radix extract is the crude extract derived from the dried root tuber of *Ampelopsis japonica* (Vitaceae), a traditional Chinese medicinal herb widely used in East Asia. It has been employed in traditional medicine primarily for its anti-inflammatory and anticancer properties, particularly in the management of colorectal cancer (CRC) and other malignancies[1]. Pharmacological studies have demonstrated that the extract exerts its effects via suppression of STAT3 signaling and Src phosphorylation, leading to reduced tumor cell viability, induction of apoptosis, and inhibition of cell migration[1]. It also possesses neuroprotective and antioxidant properties, partly due to its active polyphenolic constituents such as gallic acid, catechin, epicatechin, resveratrol, and schizandriside[1][3]. Recent research explores its use in advanced formulations, such as phytosome-encapsulated Ampelopsis radix ethanolic extracts, aiming to improve therapeutic efficacy against CRC[2]. Its mechanisms suggest potential in other indications involving inflammation and neurodegeneration, but modern drug derivatives or standardized pharmaceutical products are not yet available.

Other names

Ampelopsis Radix extractAmpelopsis RadixAJW*Ampelopsis japonica* root extractAmpelopsis japonica extract