amphiregulin

**Amphiregulin** is an endogenous epidermal growth factor family ligand and heparin-binding protein that activates **epidermal growth factor receptor** signaling, driving cellular proliferation, differentiation, tissue repair, and fibroblast activation. In the provided public sources, amphiregulin appears both as a biologic culture supplement used in assisted reproduction and as a disease-relevant signaling molecule in fibrosis and inflammatory disorders. A registered interventional fertility study at My Duc Hospital lists amphiregulin as a drug intervention in in vitro maturation media for oocytes, indicating human interventional use in an ART setting, while peer-reviewed and meeting literature describe amphiregulin as a mediator of intestinal, pulmonary, skin, and other fibrotic or inflammatory processes. It is not an approved branded medicine and is better understood as a recombinant or exogenous form of a native human growth factor used experimentally and translationally rather than as a conventional commercial therapeutic drug.

Other names

amphiregulinAREGAR