Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
amphotericin b cholesteryl sulfate complex
- Development stage
- Phase 4
- Lead developer
- InterMune
- Modality
- Nanoparticles → Drug Delivery Systems, Small Molecules
- Administration
- Intravenous
01
Overview
**Amphotericin B cholesteryl sulfate complex** is an intravenous colloidal-dispersion formulation of the polyene antifungal amphotericin B, in which amphotericin B is complexed with cholesteryl sulfate. It binds fungal-membrane ergosterol, disrupting membrane integrity and causing leakage of intracellular constituents and fungal cell death. Also known as amphotericin B colloidal dispersion, ABCD has been marketed historically as Amphotec and Amphocil; Chinese development programs led by CSPC companies include the domestic product Amphlik. Registered Chinese studies have evaluated the formulation for invasive candidiasis, invasive aspergillosis, invasive mold infection, cryptococcal meningitis, and empirical treatment of invasive fungal disease.
- Brand names
- AmphotecAmphocilAmphlik
- Other names
- amphotericin B colloidal dispersionABCDamphotericin B cholesterol sulfate complexamphotericin B cholesteryl sulfate complex for injection两性霉素B胆固醇硫酸酯复合物
02
Targets
Ergosterol
Beyond the preview
Go deeper on amphotericin b cholesteryl sulfate complex.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on amphotericin b cholesteryl sulfate complex.