Drug intelligence / Profile preview

ampicillin + cloxacillin + lactic acid bacillus

Development stage
Unknown
Lead developer
Cyper Pharma
Modality
Live Biotherapeutic Products → Microbiome Therapeutics, Small Molecules
Administration
Oral
01

Overview

Cypclox-LB is a fixed-dose combination antibiotic and probiotic product manufactured by Cyper Pharma. It contains ampicillin, a broad-spectrum aminopenicillin, and cloxacillin, a penicillinase-resistant penicillin, alongside lactic acid bacillus (Lactobacillus). The two antibiotics work synergistically to inhibit bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs); ampicillin provides coverage against a wide range of Gram-positive and Gram-negative bacteria, while cloxacillin is specifically effective against beta-lactamase-producing Staphylococci. Lactic acid bacillus is included as a probiotic to restore the natural intestinal microflora and prevent antibiotic-associated diarrhea, a common side effect of broad-spectrum antibiotic therapy. It is indicated for the treatment of various bacterial infections, including respiratory tract, skin, and soft tissue infections.

Brand names
Cypclox-LB
Other names
Ampicillin, Cloxacillin and Lactic Acid Bacillus Capsules
02

Targets

PBP1A (Penicillin-binding protein 1A)PBP2 (Penicillin-binding protein 2)

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