Drug intelligence / Profile preview

Amplivax

Development stage
Unknown
Lead developer
The Immune Response
Administration
Intramuscular, Subcutaneous
01

Overview

Amplivax is a proprietary biological adjuvant used as an immunological enhancer in therapeutic HIV vaccine studies. Specifically, it has been studied in combination with HIV-1 antigen vaccine formulations such as Remune to stimulate and augment HIV-specific immune responses in people with HIV/AIDS. Amplivax is formulated as HYB2055 and is administered in a protocol involving emulsification in incomplete Freund’s adjuvant. Its mechanism involves immune system stimulation, particularly the enhancement of CD4+ and CD8+ T cell responses to HIV antigens. The compound has been evaluated in Phase I/II and Phase III trials for its safety and efficacy as part of combination immunotherapeutic strategies[1][3][7].

Brand names
Amplivax
Other names
Amplivax HYB2055

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