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Amrta Karuna
- Development stage
- Unknown
- Lead developer
- Vopec Pharmaceuticals
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Amrta Karuna is a Siddha/Ayurveda-based multi-herbal syrup developed by Vopec Pharmaceuticals as an anti-viral and immunomodulatory formulation for viral infections, including COVID-19. It contains a proprietary combination of five anti-viral herbs from traditional Indian medicine and has been evaluated in clinical trials in India, where it reportedly reduced hospitalization days in COVID-19 patients and favorably influenced immune parameters compared with standard care. Preclinical in vitro and in silico work attributed its activity to interference with SARS-CoV-2 ACE2–spike interaction and NSP15-mediated viral replication, alongside broader immunomodulatory effects that may extend to other viral diseases such as dengue and influenza.
- Brand names
- Amrta Karuna
02
Targets
Spike-ACE2 PPI (SARS-CoV-2 spike–ACE2 interface)Nsp15 (SARS-CoV-2 non-structural protein 15)
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