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Amvalor Chrono
- Development stage
- Unknown
- Lead developer
- Arinna Lifescience
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Amvalor Chrono is an approved antiepileptic medication developed and marketed by Arinna Lifescience. It is a controlled-release (CR) tablet formulation containing a combination of sodium valproate and valproic acid. The drug functions by increasing the concentration of gamma-aminobutyric acid (GABA) in the brain, primarily through the inhibition of GABA transaminase and the stimulation of glutamate decarboxylase. It also modulates voltage-gated sodium channels and T-type calcium channels. Amvalor Chrono is indicated for the treatment of various seizure disorders, including absence, myoclonic, and generalized tonic-clonic seizures, as well as for the management of bipolar disorder and migraine prophylaxis.
- Brand names
- Amvalor Chrono
- Other names
- Sodium Valproate + Valproic Acid CR
02
Targets
NaV (Voltage-gated sodium channels)ABAT (4-aminobutyrate aminotransferase)CACNA1B (Voltage-dependent N-type calcium channel subunit alpha-1B)CaV3 (Caveolin-3)
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