Drug intelligence / Profile preview

Amviacin AP

Development stage
Unknown
Lead developer
Insmed
Modality
Small Molecules
Administration
Oral
01

Overview

Amviacin AP is a commercial generic fixed-dose combination (FDC) medication containing aceclofenac and paracetamol (acetaminophen), marketed by AMVIO (Amvia Biotech). Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) of the phenylacetic acid class that acts as a preferential inhibitor of the cyclooxygenase-2 (COX-2) enzyme, thereby reducing the synthesis of inflammatory prostaglandins. Paracetamol is a widely used analgesic and antipyretic agent that is thought to act primarily in the central nervous system by inhibiting prostaglandin synthesis. This combination is indicated for the symptomatic relief of pain and inflammation associated with musculoskeletal disorders such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It is typically administered orally in tablet form and is part of a broader portfolio of commercial generic formulations produced by the company.

Brand names
Amviacin AP
Other names
Aceclofenac + ParacetamolAceclofenac/ParacetamolAceclofenac/Acetaminophen
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)PGHS-1 (Prostaglandin G/H Synthase 1)

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