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an shen jiao tai yi zhi decoction
- Development stage
- Preclinical
- Lead developer
- Hebei Provincial Hospital of Traditional Chinese Medicine
- Administration
- Oral
01
Overview
An Shen Jiao Tai Yi Zhi decoction is a traditional Chinese medicine (TCM) herbal formula composed of multiple medicinal components: cassia twig, oyster, Salvia miltiorrhiza, keel, vinegar glans plate, Acorus gramineus, radix curcumae, paeoniae alba, and licorice[1][2]. Each herb is believed to contribute to the decoction’s effects, such as calming the mind, regulating "yin-yang" balance, improving blood circulation, and enhancing cognitive function. In clinical contexts, this decoction has been studied for sleep disorders associated with Parkinson’s disease. Proposed mechanisms include anti-inflammatory actions, modulation of neurotransmitter levels (notably norepinephrine, dopamine, 5-hydroxytryptamine), reduction of homocysteine and interleukin-1β, and improvement of sleep architecture[1]. The formula is typically administered orally as a decoction twice daily. Currently, this formula is mainly used within traditional Chinese medicine practice, and scientific evidence remains limited to clinical studies in China[1][2].
- Brand names
- an shen jiao tai yi zhi decoction
- Other names
- 安神交泰益智汤
02
Targets
DRD (Dopamine receptors)AR (Adrenergic receptors)HTR6 (5-hydroxytryptamine receptor 6)IL1B (Interleukin-1 beta)
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