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An Wei Tie
- Development stage
- Unknown
- Lead developer
- Shanghai Institute of Acupuncture, Moxibustion and Meridian
- Modality
- Small Molecules
- Administration
- Topical, Transdermal
01
Overview
An Wei Tie is a specialized traditional Chinese medicine (TCM) acupoint patch developed by the Shanghai Institute of Acupuncture and Meridian for the treatment of chronic insomnia. The patch is applied topically to specific acupoints, such as Shenmen (HT7), Anmian, and Sanyinjiao (SP6), to facilitate the transdermal absorption of herbal constituents while providing localized stimulation. The formulation typically includes sedative herbs like Semen Ziziphi Spinosae (Suan Zao Ren) and Rhizoma Chuanxiong, which are believed to modulate neurotransmitter systems, particularly by increasing gamma-aminobutyric acid (GABA) levels and regulating serotonin (5-HT) pathways in the brain. Clinical research has indicated that An Wei Tie can effectively improve sleep quality and reduce the time to sleep onset, offering a non-systemic alternative or adjunct to conventional sedative-hypnotic drugs with a lower risk of dependency and side effects.
- Brand names
- An Wei Tie
- Other names
- An-Wei-TieAnweitieAn Wei Tie Acupoint Patch
02
Targets
GABA-B (Gamma-aminobutyric acid receptor type B)5-HT (Serotonin receptors)
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