Drug intelligence / Profile preview

androstanedione

Development stage: Unknown
Modality: Small Molecules

Overview

Androstanedione (also known as 5α-androstanedione or 5alpha-androstan-3,17-dione) is a synthetic and naturally occurring steroid and an intermediate in the biosynthesis of androgens. It is classified as a small molecule with the chemical formula C19H28O2. Androstanedione acts primarily as a precursor in the metabolic pathway leading to the production of testosterone and estrogens. Its main function involves serving as a substrate for enzymes such as aldo-keto reductases that catalyze its conversion to other active steroids. It has been studied experimentally but is not approved for medical use[2].

Other names: androstanedione5alpha-androstan-3,17-dione5α-androstane-3,17-dione

Targets

AKR1C1 (Aldo-keto reductase family 1 member C1)AKR1C2 (Aldo-keto reductase family 1 member C2)AKR1C3 (Aldo-keto reductase family 1 member C3)AKR1C20 (Aldo-keto reductase family 1 member C20)

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