Drug intelligence / Profile preview

anetosacin

Development stage
Unknown
Lead developer
Anhui Global Pharmaceutical
Modality
Small Molecules
Administration
Intravenous
01

Overview

Anetosacin is a fluoroquinolone antibiotic developed by Anhui Global Pharmaceutical for the treatment of bacterial infections, specifically community-acquired pneumonia (CAP). As a member of the fluoroquinolone class, it exerts its antibacterial activity by inhibiting bacterial DNA gyrase (topoisomerase II) and topoisomerase IV. These enzymes are essential for bacterial DNA replication, transcription, repair, and recombination; their inhibition leads to the cessation of DNA synthesis and ultimately bacterial cell death. Anetosacin has been evaluated in clinical trials as an intravenous hydrochloride injection, where it was compared against levofloxacin to assess its safety and efficacy in patients with community-acquired pneumonia.

Other names
anetosacin hydrochlorideanetosacin hydrochloride injection阿内沙星
02

Targets

Topo IV (Bacterial Topoisomerase IV)DNA gyrase

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