Drug intelligence / Profile preview

angelica gigas nakai ethanol extract

Development stage
Preclinical
Lead developer
Myongji University
Administration
Oral
01

Overview

Angelica gigas Nakai ethanol extract is a high-purity plant extract derived from the roots of Angelica gigas Nakai using ethanol as the extraction solvent[1][2]. The primary active constituents are decursin and decursinol angelate, which can comprise over 90% of the purified extract[2]. This substance is studied for its antithrombotic, anti-platelet aggregation, and antioxidant effects, showing significant potential in reducing thrombus formation and preventing ischemic stroke while exhibiting lower bleeding risk compared to acetylsalicylic acid[1]. The extract also demonstrates free radical scavenging properties and potential for blood circulation improvement, anti-inflammatory, neuroprotective, kidney toxicity inhibition, and metabolic disorder protection[1][2]. It is used in research as a natural alternative for cardiovascular and circulatory disorders and is considered for pharmaceutical and nutraceutical development.

Brand names
AGE 232AGE232AGE-232
Other names
Angelica gigas Nakai ethanol extractAngelica gigas extract참당귀 에탄올 추출물
02

Targets

PGHS-1 (Prostaglandin G/H Synthase 1)

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