Drug intelligence / Profile preview

Anhui Medical Univ. VEGFR2 compound 25

Development stage
Preclinical
Lead developer
Anhui Medical University
01

Overview

Anhui Medical Univ. VEGFR2 compound 25: sourced facts only. name: "The most potent compound, compound 25, displayed single-digit nanomolar potency against VEGFR2 in biochemical assays and achieved good selectivity for other protein kinases in the kinome." [PMID:37216810]; target: "The most potent compound, compound 25, displayed single-digit nanomolar potency against VEGFR2 in biochemical assays and achieved good selectivity for other protein kinases in the kinome." [PMID:37216810]; developer: "Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, School of Pharmacy, Anhui Medical University, Hefei, 230032, Anhui Province, PR China." [PMID:37216810]; stage: "Moreover, compound 25 reduced the severity and development of adjuvant-induced arthritis in rats by inhibiting synovial VEGFR2 phosphorylation and angiogenesis." [PMID:37216810]

02

Targets

VEGFR2 (Vascular endothelial growth factor receptor 2)

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