Anhui Univ. of Science and Technology PRDX1 compound 7e

Anhui Univ. of Science and Technology PRDX1 compound 7e: sourced facts only. name: "Among them, compound 7e stood out as the most potent peroxiredoxin 1 (PRDX1) inhibitor (IC50 = 0.164 μM), which was significant super to the recognized PRDX1 inhibitor Conoidin A (IC50 = 14.80 μM) and the control compound celastrol (IC50 = 1.622 μM)." [PMID:37499289]; target: "Among them, compound 7e stood out as the most potent peroxiredoxin 1 (PRDX1) inhibitor (IC50 = 0.164 μM), which was significant super to the recognized PRDX1 inhibitor Conoidin A (IC50 = 14.80 μM) and the control compound celastrol (IC50 = 1.622 μM)." [PMID:37499289]; developer: "School of Medicine, Anhui University of Science and Technology, Huainan, 232001, China; Anhui Occupational Health and Safety Engineering Laboratory, Huainan, 232001, China." [PMID:37499289]; stage: "Most importantly, compound 7e (TGI = 77.47%) showed more considerable in vivo antitumor efficacy and less toxicity than celastrol (TGI = 71.00%)." [PMID:37499289]