Drug intelligence / Profile preview

anileridine

Development stage
Unknown
Lead developer
Merck
Modality
Small Molecules
Administration
Oral, Intravenous, Intramuscular, Subcutaneous
01

Overview

Anileridine is a synthetic opioid analgesic of the piperidine class developed by Merck & Co. in the 1950s for the treatment of moderate to severe pain. It acts primarily as a mu-type opioid receptor agonist in the central nervous system (CNS), producing analgesia by mimicking endogenous opioids and inhibiting nociceptive neurotransmitter release. Anileridine was used both as a pain reliever and as an adjunct to anesthesia but is no longer manufactured in the US or Canada. Its pharmacological effects are similar to those of morphine and meperidine but with some differences in side effect profile and duration of respiratory depression[2][4][5][6].

Brand names
Leritine
Other names
Aldineanileridine hydrochlorideanileridine dihydrochlorideanileridine HCl
02

Targets

MOR (Mu opioid receptor)

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