Drug intelligence / Profile preview

anise seed extract

Development stage
Unknown
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral, Topical
01

Overview

**Anise seed extract** is a botanical extract derived from the seeds of *Pimpinella anisum*. The extract contains diverse active constituents, notably trans-anethole, estragole, para-anisaldehyde, and methyl chavicol, which contribute to its pharmacological properties. It has traditionally been used for **digestive issues**, respiratory problems, menstrual discomfort, menopausal symptom relief, antimicrobial (antibacterial, antifungal, antiviral), antioxidant effects, anti-inflammatory action, muscle relaxant properties, and analgesia for migraine[5][1][3][4][7]. Mechanistically, the extract exhibits estrogen-like effects, muscle relaxation (tracheal and smooth muscle), inhibition of gastric acid secretion, modulation of neurotransmitters (antidepressant), and broad-spectrum antimicrobial action. Clinical evidence is strongest for the management of mild to moderate depression, protection against stomach ulcers, and reduction of menopausal hot flashes; however, large-scale trials remain limited[1][5][6][3]. The extract is typically administered orally but can also be used topically, or as an ingredient in sprays for lice removal.

Other names
aniseaniseedPimpinella anisum extractanise seed oilanise seed powder
02

Targets

ESR1 (ERα)

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