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**ANN-103** is a preclinical fixed-dose transdermal microneedle patch being developed by Anodyne Nanotech for **sarcopenic obesity**. The product combines an undisclosed glucagon-like peptide 1 receptor agonist with an undisclosed apelin receptor agonist to promote fat loss while preserving skeletal-muscle mass. It uses the HeroPatch microneedle platform for needle-free, tunable transdermal delivery of peptide biologics and is in PK/PD optimization.
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