Drug intelligence / Profile preview

anredera cordifolia extract

Development stage
Phase 1
Modality
Small Molecules
Administration
Oral, Topical
01

Overview

Anredera cordifolia extract, derived from the leaves of the plant commonly known as Binahong, is a botanical medicine widely utilized in Southeast Asian traditional medicine for its wound-healing, anti-inflammatory, and anti-diabetic properties. The extract contains a complex mixture of bioactive secondary metabolites, including flavonoids, saponins, alkaloids, and polyphenols. Its mechanism of action in wound healing involves the stimulation of fibroblast proliferation and the enhancement of collagen synthesis, which accelerates the closure of incisions and burns. Additionally, the extract exhibits hypoglycemic effects through the inhibition of alpha-glucosidase and possesses anti-inflammatory activity likely mediated by the reduction of pro-inflammatory cytokines and the scavenging of reactive oxygen species. It is primarily investigated for applications in postoperative recovery, diabetic wound management, and the treatment of hyperuricemia.

Brand names
Binahong
Other names
Anredera cordifolia leaf extractBinahong extractMadeira vine extractHeartleaf Madeira vine extract
02

Targets

XO (Xanthine Oxidoreductase)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)Sucrase-Isomaltase

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