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Anshen granules
- Development stage
- Unknown
- Lead developer
- Guangdong Provincial Hospital of Traditional Chinese Medicine
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Anshen granules is a traditional Chinese medicine (TCM) hospital preparation developed by the Guangdong Provincial Hospital of Traditional Chinese Medicine for the treatment of insomnia. The formula is designed to calm the spirit and nourish the heart, addressing the TCM patterns of heart-blood deficiency and liver-qi stagnation often associated with sleep disturbances. The primary active ingredient is typically Semen Ziziphi Spinosae (Suan Zao Ren), which contains jujubosides and flavonoids that exhibit sedative and hypnotic effects. These compounds are believed to interact with the GABAergic system, specifically modulating GABA-A receptors to enhance inhibitory neurotransmission in the brain. The preparation is used clinically to improve sleep quality, reduce sleep latency, and alleviate anxiety-related symptoms in patients. As a hospital-made medicine, it is registered and used within the Guangdong Provincial Hospital of TCM system.
- Other names
- Anshen KeliAnshen formulaAnshen
02
Targets
DRD2 (Dopamine D2 Receptor)TRPV1 (Transient receptor potential cation channel subfamily V member 1)
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