Drug intelligence / Profile preview

antarctic krill oil

Development stage
Phase 2
Lead developer
Aker BioMarine
Modality
Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Small Molecules
Administration
Oral
01

Overview

Antarctic krill oil is an extract derived from the Antarctic species of krill (Euphausia superba), a small shrimp-like marine crustacean. It is rich in omega-3 polyunsaturated fatty acids, primarily eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which are mainly bound to phospholipids rather than triglycerides as in fish oils. Antarctic krill oil also contains the antioxidant astaxanthin and choline-containing phospholipids such as phosphatidylcholine. The proposed mechanisms of action include anti-inflammatory effects via modulation of eicosanoid synthesis, reduction of blood triglyceride levels, improvement in lipid profiles, and potential antiplatelet activity that may slow blood clotting. It is marketed primarily as a dietary supplement for cardiovascular health (e.g., hyperlipidemia, hypertriglyceridemia), dry eye syndrome, osteoarthritis symptoms relief, and general wellness; however, robust clinical evidence supporting these uses remains limited[1][2][4][9].

Brand names
Kriaxanthin Antarctic Krill OilNeptune Krill Oil
Other names
krill oilarctic krill oilEuphausia superba oil
02

Targets

PPARD (Peroxisome proliferator–activated receptor delta)PPARG (Peroxisome proliferator-activated receptor gamma)PPARA (Peroxisome proliferator-activated receptor alpha)

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