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anti-BCMA CAR-T
- Development stage
- Phase 2
- Lead developer
- Shanghai HRAIN Biotechnology
- Modality
- Cell Therapies, Gene Therapies
- Administration
- Intravenous
01
Overview
Anti-BCMA CAR-T is a type of adoptive cell therapy that involves genetically engineering a patient's own T cells to express a chimeric antigen receptor (CAR) specifically designed to recognize and bind to B-cell Maturation Antigen (BCMA). BCMA is a protein commonly found on the surface of multiple myeloma cells and plasma cell leukemia cells. Once infused back into the patient, these modified CAR-T cells can identify and eliminate BCMA-expressing cancer cells, offering a targeted approach to treating hematological malignancies. This therapy has shown significant promise in patients with relapsed/refractory multiple myeloma and is being investigated for other BCMA-positive tumors.
- Other names
- Human Derived anti-BCMA CAR-T InjectionCAR-T-anti BCMACAR-BCMA T cells
02
Targets
BCMA (B-cell maturation antigen)
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