anti-CD33-ζ CAR

anti-CD33-ζ CAR refers to a type of Chimeric Antigen Receptor (CAR) T-cell therapy. It involves genetically modifying T-cells to express a CAR that specifically targets the CD33 myeloid antigen, which is commonly found on acute myeloid leukemia (AML) cells. The "ζ" (zeta) component signifies the inclusion of the CD3ζ intracellular signaling domain, essential for activating the T-cell upon binding to CD33. This engineering aims to enhance the T-cells' ability to recognize and eliminate CD33-expressing cancer cells, thereby improving anti-tumor efficacy.

Other names

CD33-CAR-TCD-33-CAR-TCD 33-CAR-Tautologous anti-CD33 CAR T-cell therapyCD33-specific CAR T-cellsCD-33-specific CAR T-cellsCD 33-specific CAR T-cells