anti-CS6 BSIgG

Anti-CS6 BSIgG is a hyperimmune bovine serum immunoglobulin G preparation generated by immunizing cattle with the colonization factor antigen CS6 from enterotoxigenic *Escherichia coli* (ETEC). The resulting antibodies are purified from bovine serum and administered orally as a passive prophylactic agent to prevent ETEC-induced diarrhea. The mechanism of action involves binding to the CS6 colonization factor on ETEC, theoretically blocking bacterial adherence to intestinal epithelial cells and preventing infection. In clinical studies, anti-CS6 BSIgG was well tolerated but did not demonstrate significant efficacy in preventing moderate-severe diarrhea following challenge with CS6-expressing ETEC strain B7A[1][3][4][5]. The product is developed and manufactured by SAB Biotherapeutics.

Other names

hyperimmune bovine serum immunoglobulin G against CS6anti-CS6 bovine serum IgGanti-CS-6 bovine serum IgGanti-CS 6 bovine serum IgG