Drug intelligence / Profile preview

anti-D + intravenous immunoglobulin + methylprednisolone + vincristine

Development stage
Preclinical
Lead developer
Grifols
Modality
Small Molecules
Administration
Intravenous, Intramuscular, Oral
01

Overview

This is a combination therapy consisting of four components: anti-D (Rho(D) immune globulin), intravenous immunoglobulin, methylprednisolone, and vincristine. This combination is likely used in the treatment of immune thrombocytopenic purpura (ITP) or other hematological disorders. Anti-D (Rho(D) immune globulin) is used to treat immune thrombocytopenic purpura in Rh-positive patients by binding to the D antigen on red blood cells. Intravenous immunoglobulin works by modulating the immune response. Methylprednisolone is a corticosteroid that reduces inflammation and suppresses the immune system. Vincristine is a vinca alkaloid that inhibits microtubule assembly and is used as an antineoplastic agent.

02

Targets

TUBB (Tubulin (alpha and beta subunits))GR (Glucocorticoid receptor)

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