anti-Fba antibody

**anti-Fba antibody** refers to an experimental antibody directed against the Fba peptide epitope derived from *Candida albicans* fructose-bisphosphate aldolase, a cell surface-associated fungal antigen studied as an immunotherapeutic target in candidiasis. In the published preclinical literature, the best-defined example is the murine IgM monoclonal antibody **E2-9**, which bound the Fba epitope on *C. albicans* and showed protective activity in mouse models of disseminated candidiasis after passive transfer. This is not an approved pharmaceutical product; rather, it is a research-stage anti-infective antibody concept associated with work from academic investigators studying vaccine and passive immunization approaches against invasive *Candida* infection.

Other names

anti-Fba antibodyanti-Fba monoclonal antibodyFba peptide-specific monoclonal antibody