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Drug intelligence / Profile preview
anti-FSTL1 monoclonal antibody
- Development stage
- Preclinical
- Lead developer
- Pharma Foods International
- Modality
- Monoclonal Antibodies → Antibody-Based Therapeutics
- Administration
- Intravenous, Subcutaneous
01
Overview
The anti-FSTL1 monoclonal antibody is an investigational biologic therapeutic developed by Pharma Foods International using its proprietary ALAgenе® antibody technology platform. It specifically targets Follistatin-like 1 (FSTL1), an extracellular glycoprotein that is often upregulated in the tumor microenvironment and involved in immune dysfunction and cancer progression. The antibody functions by blocking the FSTL1-DIP2A axis, which has been shown in preclinical models to enhance anti-tumor immunity and suppress cancer metastasis. Research indicates potential efficacy across various malignancies, including osteosarcoma and lung cancer, particularly in tumor models with increased mesenchymal stromal/stem cells (MSCs).
- Other names
- FSTL1-monoclonal antibodyFSTL-1-monoclonal antibodyFSTL 1-monoclonal antibodyanti-Follistatin-like 1 monoclonal antibodyanti-Follistatin-like1 monoclonal antibodyanti-Follistatin-like-1 monoclonal antibody
02
Targets
FSTL1 (Follistatin-like protein 1)
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