Drug intelligence / Profile preview

anti-hepatitis D antibody

Development stage
Phase 1
Lead developer
Region Midtjylland
Modality
Antibody-Based Therapeutics
Administration
Intravenous, Subcutaneous
01

Overview

Anti-hepatitis D antibody refers to a therapeutic approach utilizing antibodies to target the hepatitis D virus (HDV) in patients with chronic infection. In the context of the **SAMBA-D study** (Safety and efficacy of therapeutic antibodies targeting hepatitis D virus in patients with chronic hepatitis D infection), this intervention is being evaluated in a Phase 3 clinical trial setting. The treatment aims to neutralize the virus or prevent its entry and spread within hepatocytes, addressing the severe liver disease associated with chronic HDV, which currently has limited therapeutic options. The trial is sponsored by **Region Midtjylland** (Central Denmark Region) and involves clinical sites in Germany and Denmark.

Other names
anti-hepatitis D antibodyanti-HDV antibodytherapeutic antibodies targeting hepatitis D virus
02

Targets

HBsAg (Hepatitis B surface antigen)HDV (Hepatitis delta virus)

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