Drug intelligence / Profile preview

anti-HIV immune serum globulin

Development stage
Phase 3
Lead developer
Abbott
Modality
Recombinant Proteins and Enzymes
Administration
Intravenous, Intramuscular
01

Overview

Anti-HIV immune serum globulin is a specialized immunoglobulin preparation containing antibodies against HIV. It is derived from pooled human blood plasma with high levels of anti-HIV antibodies. Like other immunoglobulin therapies, it works by providing passive immunity and may help reduce the incidence of infections in HIV-infected patients. The preparation interacts with various components of the immune system, including cytokines, complement, and Fc receptors, potentially providing both antiviral and immunomodulatory effects.

Brand names
HIVIGLOB
Other names
human HIV immune globulinHIV-1 hyperimmune globulinHIV1 hyperimmune globulinHIV 1 hyperimmune globulinUgandan HIV hyperimmune globulinNYBC-HIVIGNABI-HIVIG
02

Targets

Env (HIV-1 envelope glycoprotein)FcγR (Low affinity immunoglobulin gamma Fc region receptor II-c)

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