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Drug intelligence / Profile preview
anti-IL-7 neutralizing monoclonal antibody
- Development stage
- Preclinical
- Modality
- Monoclonal Antibodies → Antibody-Based Therapeutics
- Administration
- Intravenous, Subcutaneous
01
Overview
Anti-IL-7 neutralizing monoclonal antibodies are biologic agents designed to bind to and neutralize interleukin-7 (IL-7), a cytokine critical for T-cell development, survival, and homeostatic proliferation. By blocking the interaction between IL-7 and its receptor (IL-7R), these antibodies inhibit downstream signaling pathways (such as JAK-STAT and PI3K-Akt), thereby suppressing T-cell-mediated immune responses. In preclinical research, anti-IL-7 neutralizing antibodies are widely used to study T-cell homeostasis, lymphopoiesis, and the role of IL-7 in autoimmune diseases, chronic inflammation, and cancer-associated bone resorption.
- Other names
- anti-IL-7 mAbanti-IL7 mAbanti-IL 7 mAbanti-IL-7 neutralizing mAbanti-IL7 neutralizing mAbanti-IL 7 neutralizing mAbanti-interleukin-7 monoclonal antibodyanti-interleukin7 monoclonal antibodyanti-interleukin 7 monoclonal antibody
02
Targets
IL7 (IL-7)
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