anti-inhibitor coagulant complex

Anti-inhibitor coagulant complex is a plasma-derived biologic medication containing a mixture of coagulation factors, including non-activated Factors II, IX, and X and activated Factor VII. It is used to treat and prevent bleeding episodes in patients with hemophilia A or B who have developed inhibitors (antibodies) to standard clotting factor replacement therapies. By providing these clotting factors, the drug helps bypass the effects of inhibitors and promotes blood clot formation. The product is administered intravenously and is indicated for both on-demand treatment of bleeding episodes as well as perioperative management in this patient population[1][2][5]. The mechanism involves supplying activated and nonactivated vitamin K-dependent clotting factors to restore hemostasis when endogenous pathways are blocked by inhibitors[6].

Brand names

FeibaFeiba NFFeiba VH ImmunoAutoplex T

Other names

antiinhibitor coagulant complex