Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
anti-mouse IL-1β monoclonal antibody
- Development stage
- Preclinical
- Lead developer
- Novartis
- Modality
- Monoclonal Antibodies → Antibody-Based Therapeutics
- Administration
- Intraperitoneal, Subcutaneous
01
Overview
Anti-mouse IL-1β monoclonal antibody is a research-grade biologic used in preclinical murine models to investigate the role of interleukin-1 beta (IL-1β) in disease pathogenesis. It serves as a surrogate for human-targeted IL-1β inhibitors like canakinumab. In research settings, such as studies on atherosclerosis and clonal hematopoiesis of indeterminate potential (CHIP), this antibody is administered to mice to evaluate how blocking the IL-1β pathway affects plaque formation, inflammatory cell recruitment, and systemic inflammation. The antibody specifically neutralizes the mouse version of the cytokine, which is a key product of the NLRP3 inflammasome and a major driver of the cytokine hypothesis of cardiovascular disease.
- Other names
- anti-mouse IL-1β mAbanti-mIL-1βIL-1β neutralizing antibody
02
Targets
IL1B (Interleukin-1 beta)
Beyond the preview
Go deeper on anti-mouse IL-1β monoclonal antibody.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on anti-mouse IL-1β monoclonal antibody.