anti-mPD-1

Anti-mPD-1 refers to monoclonal antibodies that specifically target the mouse programmed cell death protein 1 (mPD-1), a checkpoint receptor expressed on T cells. These antibodies are widely used in preclinical research involving mouse models to study immune checkpoint blockade and cancer immunotherapy. The mechanism of action involves binding to mPD-1 and blocking its interaction with its ligand, PD-L1, thereby preventing the inhibitory signaling that suppresses T-cell activation. This blockade enhances T-cell-mediated immune responses against tumors or other antigens in mice[2][4][5]. Anti-mPD-1 is not a specific pharmaceutical product for human use but rather a class of research reagents used primarily in laboratory settings for mechanistic studies and drug development targeting the PD-1/PD-L1 pathway[4][5].

Other names

anti-mouse PD-1anti–mouse programmed cell death protein 1 antibody