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Anti-pseudomonas antibodies-University Hospital, Grenoble is a research program led by the University Hospital, Grenoble (Centre Hospitalier Universitaire de Grenoble) focused on the development of human monoclonal antibodies for the treatment of Pseudomonas aeruginosa infections. The program utilizes a prospective study to isolate therapeutic antibodies from the B lymphocytes of patients, particularly those with cystic fibrosis, who have been previously infected or colonized by the pathogen. These recombinant biologics are designed to provide an alternative to conventional antibiotics, specifically targeting multi-drug resistant (MDR) strains that are prevalent in hospital settings. The research aims to identify functional antibodies from patient sera and clone them to produce effective anti-infective therapies.
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