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anti-R110 monoclonal antibody

Development stage: Preclinical
Lead developer: SinABiomedics
Modality: Monoclonal Antibodies → Antibody-Based Therapeutics

Overview

The anti-R110 monoclonal antibody is a specialized diagnostic and therapeutic candidate developed by SinABiomedics. It specifically targets the IGLV3-21R110 (R110) biomarker, a unique B-cell light-chain rearrangement found in a subset of patients with high-risk Chronic Lymphocytic Leukemia (CLL). Currently, the antibody is employed as a diagnostic reagent for the identification of R110-positive CLL cells via flow cytometry. SinABiomedics is also advancing a therapeutic concept that leverages this antibody's specificity to selectively target and eliminate malignant CLL cells, potentially offering a precision medicine approach for patients harboring this specific biomarker.

Other names: anti-IGLV3-21R110 antibodyanti-IGLV-3-21R110 antibodyanti-IGLV 3-21R110 antibodyR110 antibodyR-110 antibodyR 110 antibody

Targets

IGLV3-21R110 (Immunoglobulin lambda variable 3-21 R110 neoepitope)

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