Drug intelligence / Profile preview

anti-rabies monoclonal antibodies (Indian Immunologicals)

Development stage
Preclinical
Lead developer
Indian Immunologicals
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Administration
Intramuscular
01

Overview

Indian Immunologicals is developing a bi-valent human monoclonal antibody cocktail intended for rabies post-exposure prophylaxis (PEP). This biologic therapeutic modality is designed to neutralize the rabies virus by targeting the rabies glycoprotein, thereby preventing the virus from entering host cells. It is intended as a passive immunotherapy alternative to traditional rabies immunoglobulins (RIG) derived from equine or human plasma, offering a potentially safer and more scalable solution for preventing the onset of rabies following exposure.

Brand names
TwinrabRabiMabs
Other names
Rabies mAbsbi-valent human monoclonal antibody for rabies
02

Targets

RABV-G (Rabies virus glycoprotein)

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