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Anti-Snake Venom Serum (Monoclonal Antibody Cocktail)
- Development stage
- Preclinical
- Lead developer
- Mediclone Biotech
- Modality
- Monoclonal Antibodies → Antibody-Based Therapeutics
- Administration
- Intravenous
01
Overview
Anti-Snake Venom Serum (Monoclonal Antibody Cocktail) is a preclinical-stage therapeutic being developed by Mediclone Biotech for the treatment of snake envenomation. This product is designed as a recombinant alternative to traditional animal-derived antivenoms, which are typically produced by immunizing horses or sheep. By utilizing a cocktail of monoclonal antibodies, the therapy aims to specifically target and neutralize the diverse toxins present in snake venom while minimizing the adverse immune reactions, such as serum sickness and anaphylaxis, often associated with heterologous animal proteins. The development of this monoclonal cocktail is supported by the Department of Biotechnology, Government of India, as part of an effort to modernize antivenom production and eliminate the need for large-scale animal immunization.
- Other names
- Anti-Snake Venom SerumMonoclonal Antibody Cocktail for Snake EnvenomationMediclone ASVS Monoclonal Cocktail
02
Targets
SVMP (Snake venom metalloproteinase)CTX (Cholera toxin)3FTx (Snake venom three-finger neurotoxin)SVSP (Snake venom serine protease)svPLA2 (Snake venom phospholipase A2)
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