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anti-TSH receptor monoclonal antibody
- Development stage
- Preclinical
- Lead developer
- AV7
- Modality
- Monoclonal Antibodies → Antibody-Based Therapeutics
- Administration
- Intravenous, Intramuscular
01
Overview
**Anti-TSH receptor monoclonal antibody** refers to a putative monoclonal antibody therapeutic directed against the thyroid-stimulating hormone receptor, intended to block pathogenic autoantibody signaling at TSHR in disorders such as Graves' disease and thyroid eye disease. Based on the provided context, it appears to be associated with Av7 Limited, but the available name is descriptive rather than a clearly established unique drug identifier, and no confirmed INN, sponsor code, or brand name could be established from the information provided. The presumed mechanism would be antagonism or functional blockade of TSHR signaling to reduce thyroid stimulation and downstream autoimmune disease activity.
- Other names
- anti-TSH receptor monoclonal antibodyanti-thyroid-stimulating hormone receptor monoclonal antibodyTSH receptor monoclonal antibody
02
Targets
TSHR (Thyroid-stimulating hormone receptor)
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