Drug intelligence / Profile preview

antibiotics + levocetirizine + oxymetazoline

Development stage
Unknown
Lead developer
UCB
Modality
Small Molecules
Administration
Oral, Intranasal
01

Overview

This is a combination drug product containing three active ingredients: - **Antibiotics** (class of drugs used to treat bacterial infections; specific antibiotic not specified) - **Levocetirizine** (a second-generation antihistamine that selectively inhibits peripheral H1 receptors, reducing symptoms of allergic rhinitis and urticaria by blocking the action of histamine[6][8][9]) - **Oxymetazoline** (a topical nasal decongestant that acts as an alpha-1A adrenoceptor agonist, causing vasoconstriction in the nasal mucosa to relieve congestion[2][7]) The combination is likely intended for symptomatic relief in upper respiratory tract infections or allergic conditions where both infection and allergy symptoms are present, such as acute rhinosinusitis or severe allergic rhinitis with secondary bacterial infection. The precise mechanism will depend on the specific antibiotic included.

02

Targets

HRH1 (Histamine H1 Receptor)PBP (Penicillin-binding protein family)ADRA1A (α1A)

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