Drug intelligence / Profile preview

antimony potassium tartrate

Development stage
Discontinued
Modality
Small Molecules
Administration
Intravenous, Oral, Topical
01

Overview

Antimony potassium tartrate is a small molecule compound historically used as a schistosomicide and for the treatment of other parasitic diseases such as leishmaniasis and trypanosomiasis. It acts as a potent emetic and has been associated with significant toxicity, including lethal cardiac effects. The mechanism of action is not fully understood but may involve disruption of thiol proteins via binding to sulfhydryl groups. Its use in medicine has largely been discontinued due to severe side effects and the development of safer alternatives like praziquantel and pentavalent antimonials. Antimony potassium tartrate is now primarily used in industrial applications or as a chemical reagent[1][2][3][4].

Other names
potassium antimonyl tartratepotassium antimontarteratetartar emeticpotassium antimony tartrate
02

Targets

GSH (Glutathione)

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