Drug intelligence / Profile preview

antisense oligonucleotide targeting MaTAR25

Development stage
Preclinical
Modality
MicroRNA (miRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Antisense Oligonucleotides (ASOs) → Long RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Modified DNA Oligonucleotides → Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics, Single-strand DNA → Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics, Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Administration
Intravenous, Subcutaneous, Intramuscular
01

Overview

An **antisense oligonucleotide targeting MaTAR25** is an experimental RNA therapeutic designed to suppress the long noncoding RNA **MaTAR25**, a mammary tumor associated RNA implicated in breast cancer biology. Based on the name, the intended mechanism is sequence-specific hybridization to MaTAR25 RNA leading to target knockdown, typically through RNase H-mediated degradation or steric blockade of RNA function, with the goal of reducing tumor growth and metastatic behavior. Publicly available drug-level development details such as a unique nonproprietary name, sponsor, formulation, route, manufacturing source, or clinical development program are not clearly established from the provided name alone, so this appears to describe a preclinical research antisense construct rather than a well-defined named pharmaceutical product.

Other names
MaTAR25 antisense oligonucleotideMaTAR-25 antisense oligonucleotideMaTAR 25 antisense oligonucleotideantisense oligonucleotide targeting MaTAR25
02

Targets

MaTAR25 (Mammary tumor associated RNA 25)

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