Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
This is a combination immunosuppressive regimen consisting of six different immunomodulatory agents. The combination includes: - **Antithymocyte globulin (ATG)**: A polyclonal antibody preparation that targets T-cells, leading to T-lymphocyte cell death via complement-mediated cytotoxicity or apoptosis. - **Daclizumab**: A humanized monoclonal antibody that targets the IL-2 receptor. - **Etanercept**: A dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton tumor necrosis factor receptor linked to the Fc portion of human IgG1. It binds specifically to tumor necrosis factor (TNF) and modulates biological processes induced or regulated by TNF. - **Mycophenolate mofetil (MMF)**: An immunosuppressant that inhibits inosine monophosphate dehydrogenase, blocking T and B lymphocyte proliferation. - **Sirolimus**: An mTOR inhibitor that prevents activation of T cells and B cells by inhibiting their response to interleukin-2. - **Tacrolimus**: A calcineurin inhibitor that prevents T-cell activation. This combination regimen is likely used in the context of organ transplantation or severe autoimmune conditions to provide comprehensive immunosuppression through multiple complementary mechanisms.
Beyond the preview
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Follow clinical development from study design and recruitment through results.
Explore development by indication, patient population, and geography.
Trace asset ownership, licensing agreements, and commercial partnerships.
Explore the patent landscape and regulatory exclusivity around an asset.
Compare development programs by target, modality, and indication.
Connect source evidence and development news to your research questions.
See how Gosset can support your research on antithymocyte globulin + daclizumab + etanercept + mycophenolate mofetil + sirolimus + tacrolimus.