antrodia camphorata extract

**Antrodia camphorata extract** is a botanical drug derived from the medicinal mushroom *Antrodia camphorata*, also known as *Antrodia cinnamomea*. It is a complex natural-product mixture rather than a single defined small molecule, and reported preparations contain ergostane- and lanostane-type triterpenoids, polysaccharides, maleic and succinic acid derivatives, benzoquinone derivatives, lignans, and benzenoid compounds. A specific clinical-stage product is **LEAC-102**, which has undergone a first-in-human Phase I study in healthy volunteers. Preclinical literature attributes pleiotropic anti-inflammatory, hepatoprotective, neuroprotective, and antineoplastic effects to these extracts, with reported modulation of pathways including NF-kappaB and COX-2 and regulation of apoptosis-associated proteins such as the Bcl-2 family. The overall mechanism is therefore best understood as multi-component pathway modulation typical of a botanical extract, with exploratory development in oncology and other disease areas rather than a single validated target-indication pair.

Brand names

MEDIACE

Other names

Antrodia cinnamomea extractAntrodia camphorata extract