Drug intelligence / Profile preview

Anzy

Development stage
Unknown
Lead developer
Thrift Pharmaceuticals
Modality
Replacement Enzymes → Therapeutic Enzymes → Recombinant Proteins and Enzymes, Small Molecules
Administration
Oral
01

Overview

Anzy (also marketed as Anzy-HS) is an approved oral combination therapy developed and marketed by Thrift Pharmaceuticals for the treatment of indigestion, bloating, flatulence, and pancreatic insufficiency. The formulation combines pancreatin, bile constituents, and activated dimethicone to support comprehensive digestive function. Pancreatin supplies key pancreatic enzymes—lipase, amylase, and protease—to break down dietary fats, starches, and proteins into absorbable nutrients. Bile constituents assist in the emulsification and absorption of lipids, while activated dimethicone acts physically as a surfactant to reduce the surface tension of gastrointestinal gas bubbles, facilitating their coalescence and expulsion to relieve abdominal discomfort.

Brand names
AnzyAnzy-HS
Other names
activated dimethicone + bile constituents + pancreatinactivated dimethicone + bile extract + pancreatindimethicone + bile constituents + pancreatinpancreatin + bile constituents + activated dimethicone
02

Targets

CTRC (Chymotrypsin C)PNLIP (Pancreatic triacylglycerol lipase)PRSS1 (Trypsin family)AMY (Pancreatic alpha-amylase)

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