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AOP-P1 is a natural bioactive peptide currently under clinical investigation for the treatment of melasma. Developed by the First Affiliated Hospital of Kunming Medical University, the drug is formulated as a topical solution, typically dissolved in a 20% propylene glycol vehicle. AOP-P1 is characterized as an antioxidant peptide (AOP) that aims to mitigate hyperpigmentation by addressing oxidative stress and potentially modulating melanogenesis pathways. It is being evaluated in parallel-group, split-face interventional studies to determine its safety, tolerability, and cosmetic efficacy in reducing the severity of melasma in women.
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