Drug intelligence / Profile preview

AP10

Development stage: Preclinical
Lead developer: Aprogen
Modality: RNA Aptamers → RNA Therapeutics → Nucleic Acid Therapeutics, DNA Aptamers → DNA Therapeutics → Nucleic Acid Therapeutics

Overview

AP10 is a G-quadruplex DNA aptamer that has been designed in silico to target the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein. This aptamer is being investigated for its potential in both the diagnosis and therapeutic intervention of SARS-CoV-2 infection by blocking the virus's ability to bind to host cells.

Targets

CD43 (CD43 antigen)SARS-CoV-2 spike

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